You are watching: A mutation that results in a single amino acid substitution in the active site of an enzyme
Transcribed photo text: A mutation that outcomes in a single amino mountain substitution in a an ar of the enzyme external of the energetic site will virtually always damage the task of the enzyme. May change the optimal pH for the enzyme. May transform the ability of a competitive inhibitor to bind to the enzyme. Will often readjust the substrate specificity that the enzyme. Once the ribosome will a stop codon top top the mRNA, no corresponding tRNA enters the A site. If the translate into reaction to be to be experimentally stopped at this point, i beg your pardon of the adhering to sets of structures would you have the ability to isolate indigenous the cell? separated ribosom subunits, a polypeptide, and totally free tRNA an assembled ribosome v a separated polypeptide an assembled ribosome through a polypeptide attached come the tRNA in the website separated ribosomal subunits through a polypeptide attached to the tRNA The makers of the dietary supplement SlimNFit have come under strike from consumer who claim that the supplement does not deliver on the advertised claims to contain enzymes that boost metabolism and also build lean muscle.\" Additionally, number of consumers have actually been hospitalized all with damage to the liver and kidneys together a an outcome of taking this supplement. Together a dietary supplement, SlimNFit is not subject to FDA regulations and also is not required to disclose the proprietary blend it cases will help consumers shed weight. A representative native the SlimNFit manufacturer released a statement the they room investigating the link in between the chemistry in their proprietary mix and feasible adverse effects. They claim no liability because that the sick individuals since it is composed on all commodities that consumers should consult their physician prior to beginning any new supplement or new health regime. An elevation lab evaluate SlimNFit's clinical trials and listed that all affiliated participants in the psychological were professional or semi-professional athletes. In 1-2 complete sentences, define why the clinical trial conducted by SlimNFit is an instance of poor experimental design.
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All participants were asked to take two servings the the Slim N Trim complement per day and also record their outcomes each week. Why could this experimental design be problematic?